molecular and genetic information on Caenorhabditis elegans and related species
Tutorial and training materials by OpenHelix
| Learn to use WormBase, the primary resource for molecular and genetic information on Caenorhabditis elegans and related species. This resource contains not only genomic data but also has information on strains, phenotypes, cell and gene expression, and discussion forums on the C. elegans community. This all-inclusive resource is a critical tool for those using nematodes as a model organism for their research. Note: The WormBase team has released a new interface, and we will update our materials to reflect this soon. The current material here refers to the legacy site, which remains accessible from http://legacy.wormbase.org/ at this time. | Advertisement:
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You'll learn:
- to perform Quick Searches and navigate gene summary pages
- to browse genetic features within the context of the entire chromosome
- to construct complex queries across various sets of data stored within WormBase
- to perform nucleotide or amino acid sequence homology searches
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Recent BioMed Central research articles citing this resourceFélix Marie-Anne et al., Species richness, distribution and genetic diversity of Caenorhabditis nematodes in a remote tropical rainforest Evolutionary ecology and behaviour. BMC Evolutionary Biology (2013) doi:10.1186/1471-2148-13-10 Fazekas Dávid et al., SignaLink 2 – a signaling pathway resource with multi-layered regulatory networks Methods, software and technology. BMC Systems Biology (2013) doi:10.1186/1752-0509-7-7 Maxwell Sara et al., The SFT-1 and OXA-1 respiratory chain complex assembly factors influence lifespan by distinct mechanisms in C. elegans. Longevity Healthspan (2013) doi:10.1186/2046-2395-2-9 Caylor C Raymond et al., The Caenorhabditis elegans voltage-gated calcium channel subunits UNC-2 and UNC-36 and the calcium-dependent kinase UNC-43/CaMKII regulate neuromuscular junction morphology Joshua R Sanes. Neural Development (2013) doi:10.1186/1749-8104-8-10 Hirani Nisha et al., A simplified counter-selection recombineering protocol for creating fluorescent protein reporter constructs directly from C. elegans fosmid genomic clones Genetic engineering in animals and animal cell systems. BMC Biotechnology (2013) doi:10.1186/1472-6750-13-1 |
More about the resource:
WormBase was created and is maintained by an international consortium of scientists. The resource is currently supported by grants from the National Human Genome Research Institute at the US National Institutes of Health and the British Medical Research Council. WormBase is updated continuously, with new content available regularly. Topics presented on WormBase range from basic protein characteristics and molecular biology to classical genetics. This database contains remarkable sequence, SNP, and allele data. All information is freely accessible to the public and available for download in various formats.
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