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OpenHelix

Tools for Comparative Genomics

Tutorial and training materials by OpenHelix

Learn to use VISTA from the Genomics Division of Lawrence Berkeley National Laboratory. VISTA provides a way to examine the data from many genomes, with extensive annotation for various data types including known genes, predicted genes, SNPs, comparative multi-species analysis and much more. VISTA also contains excellent sequence alignment and visualization tools with capacity for long sequences. Use VISTA as a primary resource for your comparative genomics research needs.
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You'll learn:

  • how to examine pre-computed relationships among a variety of species
  • ways of submitting and analyzing sequences of your own in VISTA
  • how to discover possible regulatory transcription factor binding sites in your favorite genes
  • to compare genomic sequences with customizable graphical representations and many other output options


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Recent BioMed Central research articles citing this resource

Simmons R Christopher et al., Rheumatoid arthritis-associated polymorphisms are not protective against Alzheimer''''s disease. Molecular Neurodegeneration (2011) doi:10.1186/1750-1326-6-33

Baker H Richard et al., The Enhancer of split complex arose prior to the diversification of schizophoran flies and is strongly conserved between Drosophila and stalk-eyed flies (Diopsidae). BMC Evolutionary Biology (2011) doi:10.1186/1471-2148-11-354

Alikhan Nabil-Fareed et al., BLAST Ring Image Generator (BRIG): simple prokaryote genome comparisons. BMC Genomics (2011) doi:10.1186/1471-2164-12-402

Shaw Lisa et al., Paramedic Initiated Lisinopril For Acute Stroke Treatment (PIL-FAST): study protocol for a pilot randomised controlled trial. Trials (2011) doi:10.1186/1745-6215-12-152

Saski A Christopher et al., New genomic resources for switchgrass: a BAC library and comparative analysis of homoeologous genomic regions harboring bioenergy traits. BMC Genomics (2011) doi:10.1186/1471-2164-12-369

More about the resource:

VISTA is a powerful comparative genomics system which may lead to discoveries of medical importance. The VISTA family of tools is developed and hosted at Genomics Division of Lawrence Berkeley National Laboratory. This collaborative effort is supported by supported by the Programs for Genomic Applications grant from the NHLBI/NIH and the Office of Biological and Environmental Research, Office of Science, US Department of Energy.


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The materials and slides offered can not be resold or used for profit purposes. Reproduction, distribution and/or use is strictly limited to instructional purposes only and can not be used for for monetary gain or wide distribution.
Copyright 2009, OpenHelix, LLC.

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