National Institute for Environmental Health Sciences Environmental Genome Project (EGP) SNPs
Tutorial and training materials by OpenHelix
|Learn to use NIEHS SNPs Environmental Genome Program at the University of Washington. NIEHS SNPs has systematically identified and genotyped single nucleotide polymorphisms (SNPs) in environmental response genes. This data has resulted in the characterization of many new variations that will greatly help research into disease genes that respond to environmental stimulus. The NIEHS SNPs site contains the data generated by this project with links to other resources to better research and understand the human variation in environment response genes. The NIEHS SNPs website contains data generated by this project, and links to other resources enabling better research and understanding of human variation in environmental response genes.|
- about the NIEHS SNPs project
- how to access NIEHS SNPs data from the NEIHS SNPs home
- how to analyze the data using several databases and resources
This tutorial is a part of the tutorial group UW SNP resources. You might find the other tutorials in the group interesting:
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Recent BioMed Central research articles citing this resource
Bains K Ripudaman et al., Molecular diversity and population structure at the Cytochrome P450 3A5 gene in Africa Human population genetics. BMC Genetics (2013) doi:10.1186/1471-2156-14-34
Casals Ferran et al., Genetic adaptation of the antibacterial human innate immunity network. BMC Evolutionary Biology (2011) doi:10.1186/1471-2148-11-202
Sicotte Hugues et al., SNPPicker: High quality tag SNP selection across multiple populations. BMC Bioinformatics (2011) doi:10.1186/1471-2105-12-129
Cagliani Rachele et al., Balancing selection is common in the extended MHC region but most alleles with opposite risk profile for autoimmune diseases are neutrally evolving. BMC Evolutionary Biology (2011) doi:10.1186/1471-2148-11-171
Pankratz V Shane et al., Associations between SNPs in candidate immune-relevant genes and rubella antibody levels: a multigenic assessment. BMC Immunology (2010) doi:10.1186/1471-2172-11-48
More about the resource:
NIEHS SNPs, is a collaborative project housed at the University of Washington and supported by the National Institute of Environmental Health Sciences. Related SNP data can also be found at SeattleSNPs and the Genome Variation Server (GVS). The stated long term goal of this project is to “characterize how specific human genetic variations, or polymorphisms, contribute to environmentally induced disease susceptibility”.
The materials and slides offered can not be resold or used for profit purposes. Reproduction, distribution and/or use is strictly limited to instructional purposes only and can not be used for for monetary gain or wide distribution.
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