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OpenHelix

A resource for the genes, genome and molecular biology of Drosophila melanogaster and related species.

Tutorial and training materials by OpenHelix

Learn to use FlyBase, the primary resource for molecular and genetic information on the Drosophilidae. The essential database for researchers working with the Fruit Fly, FlyBase, provides tools for genetic and proteomic analysis, numerous search tools, sequence data, gene information, and data mining tools. This website, also provides easy access to BLAST, GBrowse, QueryBuilder, TermLink and ImageBrowse. Large Data queries can also be handled with Batch Download options.
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You'll learn:

  • to perform Quick Searches and navigate gene summary pages
  • to browse genetic features within the context of the entire chromosome
  • to construct complex queries across various sets of data stored within FlyBase
  • to perform nucleotide or amino acid sequence homology searches


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Recent BioMed Central research articles citing this resource

Potier Delphine et al., Identification of cis-regulatory modules encoding temporal dynamics during development Multicellular invertebrate genomics. BMC Genomics (2014) doi:10.1186/1471-2164-15-534

Jiang Hongshan et al., Skewer: a fast and accurate adapter trimmer for next-generation sequencing paired-end reads Sequence analysis (methods). BMC Bioinformatics (2014) doi:10.1186/1471-2105-15-182

Chen Linan et al., Global regulation of mRNA translation and stability in the early Drosophila embryo by the Smaug RNA-binding protein. Genome Biology (2014) doi:10.1186/gb-2014-15-1-r4

Lu Zhipeng et al., RIP-seq analysis of eukaryotic Sm proteins identifies three major categories of Sm-containing ribonucleoproteins. Genome Biology (2014) doi:10.1186/gb-2014-15-1-r7

Blumenstiel P Justin et al., Whole genome sequencing in Drosophila virilis identifies Polyphemus , a recently activated Tc1-like transposon with a possible role in hybrid dysgenesis. Mobile DNA (2014) doi:10.1186/1759-8753-5-6

More about the resource:

FlyBase is maintained by an international consortium of scientists and is funded by grants from the U.S. National Institutes of Health (NIH), the Indiana Genomics Initiative, USA, and the Medical Research Council, UK. FlyBase is freely available to the public and contains the most accurate, up to date information and news concerning Drosophilidae. This site allows quick access to information including allele and RNAi phenotypes, nucleotide and amino acid sequences, genetic interaction maps, and reagent availability.


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The materials and slides offered can not be resold or used for profit purposes. Reproduction, distribution and/or use is strictly limited to instructional purposes only and can not be used for for monetary gain or wide distribution.
Copyright 2009, OpenHelix, LLC.

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