UniProt, Universal Protein Resource
Tutorial and training materials by OpenHelix
|Learn to use the UniProt Knowledgebase, which has detailed curated information about known proteins, with predictions and computational assignments for both characterized and uncharacterized proteins. The UniRef layer provides clustered handy links to related proteins. UniParc archive records collect non-redundant but complete collections of protein sequence data. This tutorial will explore each type of record--UniProt, UniRef, and UniParc, and examine available search strategies. This resource is a foundational tool for proteomics research.|
- to perform text searches for relevant protein information
- to search with sequences as a starting point
- to understand the different types of UniProt records
- to create multi-sequence alignments from protein records using Clustal
Recent BioMed Central research articles citing this resource
Elenis Evangelia et al., The histidine-rich glycoprotein A1042G polymorphism and recurrent miscarriage: a pilot study. Reproductive Biology and Endocrinology (2014) doi:10.1186/1477-7827-12-70
Baier Herbert et al., ISAAC - InterSpecies Analysing Application using Containers Sequence analysis (applications). BMC Bioinformatics (2014) doi:10.1186/1471-2105-15-18
Calla Bernarda et al., A genomic perspective to assessing quality of mass-reared SIT flies used in Mediterranean fruit fly ( Ceratitis capitata ) eradication in California Multicellular invertebrate genomics. BMC Genomics (2014) doi:10.1186/1471-2164-15-98
Komeil Doaa et al., Comparative secretome analysis of Streptomyces scabiei during growth in the presence or absence of potato suberin. Proteome Science (2014) doi:10.1186/1477-5956-12-35
Peng Wei et al., Improving protein function prediction using domain and protein complexes in PPI networks Methods, software and technology. BMC Systems Biology (2014) doi:10.1186/1752-0509-8-35
More about the resource:
The UniProt Resource which is a centralized database for protein sequences and data, comes from the UniProt Consortium, a team consisting of members of the Swiss Bioinformatics Institute (SIB), the European Bioinformatics Institute (EBI), and the Protein Information Resource (PIR). These groups have come together to create a comprehensive and authoritative protein data resource for researchers.
The materials and slides offered can not be resold or used for profit purposes. Reproduction, distribution and/or use is strictly limited to instructional purposes only and can not be used for for monetary gain or wide distribution.
Copyright 2009, OpenHelix, LLC.