UniProt, Universal Protein Resource
Tutorial and training materials by OpenHelix
|Learn to use the UniProt Knowledgebase, which has detailed curated information about known proteins, with predictions and computational assignments for both characterized and uncharacterized proteins. The UniRef layer provides clustered handy links to related proteins. UniParc archive records collect non-redundant but complete collections of protein sequence data. This tutorial will explore each type of record--UniProt, UniRef, and UniParc, and examine available search strategies. This resource is a foundational tool for proteomics research.|
- to perform text searches for relevant protein information
- to search with sequences as a starting point
- to understand the different types of UniProt records
- to create multi-sequence alignments from protein records using Clustal
Recent BioMed Central research articles citing this resource
Gabaldón Toni et al., Comparative genomics of emerging pathogens in the Candida glabrata clade Comparative and evolutionary genomics. BMC Genomics (2013) doi:10.1186/1471-2164-14-623
Lavergne Vincent et al., Systematic interrogation of the Conus marmoreus venom duct transcriptome with ConoSorter reveals 158 novel conotoxins and 13 new gene superfamilies Transcriptomics. BMC Genomics (2013) doi:10.1186/1471-2164-14-708
Mohamed Emida et al., Enhanced expression of a 35 kDa fragment of inter-alpha-trypsin inhibitor H4 in sera of healthy pregnant women and patients with hydatidiform mole. Biomarker Research (2013) doi:10.1186/2050-7771-1-19
Zhang Bin et al., Identification of Enolase 1 and Thrombospondin-1 as serum biomarkers in HBV hepatic fibrosis by proteomics. Proteome Science (2013) doi:10.1186/1477-5956-11-30
Weikard Rosemarie et al., Identification of novel transcripts and noncoding RNAs in bovine skin by deep next generation sequencing Non-human and non-rodent vertebrate genomics. BMC Genomics (2013) doi:10.1186/1471-2164-14-789
More about the resource:
The UniProt Resource which is a centralized database for protein sequences and data, comes from the UniProt Consortium, a team consisting of members of the Swiss Bioinformatics Institute (SIB), the European Bioinformatics Institute (EBI), and the Protein Information Resource (PIR). These groups have come together to create a comprehensive and authoritative protein data resource for researchers.
The materials and slides offered can not be resold or used for profit purposes. Reproduction, distribution and/or use is strictly limited to instructional purposes only and can not be used for for monetary gain or wide distribution.
Copyright 2009, OpenHelix, LLC.