UniProt, Universal Protein Resource
Tutorial and training materials by OpenHelix
|Learn to use the UniProt Knowledgebase, which has detailed curated information about known proteins, with predictions and computational assignments for both characterized and uncharacterized proteins. The UniRef layer provides clustered handy links to related proteins. UniParc archive records collect non-redundant but complete collections of protein sequence data. This tutorial will explore each type of record--UniProt, UniRef, and UniParc, and examine available search strategies. This resource is a foundational tool for proteomics research.|
- to perform text searches for relevant protein information
- to search with sequences as a starting point
- to understand the different types of UniProt records
- to create multi-sequence alignments from protein records using Clustal
Recent BioMed Central research articles citing this resource
Rienth Markus et al., Day and night heat stress trigger different transcriptomic responses in green and ripening grapevine ( vitis vinifera ) fruit Plant-abiotic interactions. BMC Plant Biology (2014) doi:10.1186/1471-2229-14-108
Qi Baiyan et al., De novo sequencing, assembly, and analysis of the Taxodium ‘Zhongshansa’ roots and shoots transcriptome in response to short-term waterlogging. BMC Plant Biology (2014) doi:10.1186/s12870-014-0201-y
Peffers J Mandy et al., Matrix assisted laser desorption ionization mass spectrometry imaging identifies markers of ageing and osteoarthritic cartilage. Arthritis Research Therapy (2014) doi:10.1186/ar4560
Montanini Barbara et al., Non-exhaustive DNA methylation-mediated transposon silencing in the black truffle genome, a complex fungal genome with massive repeat element content. Genome Biology (2014) doi:10.1186/s13059-014-0411-5
Han Dohyun et al., Characterization of the membrane proteome and N-glycoproteome in BV-2 mouse microglia by liquid chromatography-tandem mass spectrometry Proteomics. BMC Genomics (2014) doi:10.1186/1471-2164-15-95
More about the resource:
The UniProt Resource which is a centralized database for protein sequences and data, comes from the UniProt Consortium, a team consisting of members of the Swiss Bioinformatics Institute (SIB), the European Bioinformatics Institute (EBI), and the Protein Information Resource (PIR). These groups have come together to create a comprehensive and authoritative protein data resource for researchers.
The materials and slides offered can not be resold or used for profit purposes. Reproduction, distribution and/or use is strictly limited to instructional purposes only and can not be used for for monetary gain or wide distribution.
Copyright 2009, OpenHelix, LLC.