UniProt, Universal Protein Resource
Tutorial and training materials by OpenHelix
|Learn to use the UniProt Knowledgebase, which has detailed curated information about known proteins, with predictions and computational assignments for both characterized and uncharacterized proteins. The UniRef layer provides clustered handy links to related proteins. UniParc archive records collect non-redundant but complete collections of protein sequence data. This tutorial will explore each type of record--UniProt, UniRef, and UniParc, and examine available search strategies. This resource is a foundational tool for proteomics research.|
- to perform text searches for relevant protein information
- to search with sequences as a starting point
- to understand the different types of UniProt records
- to create multi-sequence alignments from protein records using Clustal
Recent BioMed Central research articles citing this resource
Folkman Lukas et al., Towards sequence-based prediction of mutation-induced stability changes in unseen non-homologous proteins Selected articles from the Twelfth Asia Pacific Bioinformatics Conference (APBC 2014): Genomics The Twelfth Asia Pacific Bioinformatics Conference (APBC 2014). BMC Genomics (2014) doi:10.1186/1471-2164-15-S1-S4
Yang Yanfang et al., Genome sequencing and analysis of the paclitaxel-producing endophytic fungus Penicillium aurantiogriseum NRRL 62431 Comparative and evolutionary genomics. BMC Genomics (2014) doi:10.1186/1471-2164-15-69
Whelehan J Cormac et al., Characterisation and expression profile of the bovine cathelicidin gene repertoire in mammary tissue Non-human and non-rodent vertebrate genomics. BMC Genomics (2014) doi:10.1186/1471-2164-15-128
Fatima Attia et al., Alterations in hepatic miRNA expression during negative energy balance in postpartum dairy cattle Non-human and non-rodent vertebrate genomics. BMC Genomics (2014) doi:10.1186/1471-2164-15-28
Tang Jing et al., Proteomic profiling of the phosphoproteins in the rat thalamus, hippocampus and frontal lobe after propofol anesthesia General pharmacology and pharmacokinetics. BMC Anesthesiology (2014) doi:10.1186/1471-2253-14-3
More about the resource:
The UniProt Resource which is a centralized database for protein sequences and data, comes from the UniProt Consortium, a team consisting of members of the Swiss Bioinformatics Institute (SIB), the European Bioinformatics Institute (EBI), and the Protein Information Resource (PIR). These groups have come together to create a comprehensive and authoritative protein data resource for researchers.
The materials and slides offered can not be resold or used for profit purposes. Reproduction, distribution and/or use is strictly limited to instructional purposes only and can not be used for for monetary gain or wide distribution.
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