HapMap, a database and analysis resource of human variation
Tutorial and training materials by OpenHelix
|Learn to use HapMap, a database and analysis resource of human variation. The HapMap project identified and cataloged genetic variation in human beings in four populations with African, Asian, and European ancestry. This freely available database and variation browser contains much of the known variation of the Human genome and researchers can use the data to determine variations that affect health, disease, and individual responses to medications and environmental factors. Learn to use the genome browser associated with this project to view HapMap data, retrieve genotypes and find frequencies for genomic regions.|
- to find SNPs of interest with advanced searching
- how to determine linkage disequilibrium between SNPs
- how to find candidate tag SNPs to better design genotyping assays
- where to download and how to use the HaploView software for deeper SNP analysis
View additional tutorials for resources in
Recent BioMed Central research articles citing this resource
Kuan Valerie et al., DHCR7 mutations linked to higher vitamin D status allowed early human migration to Northern latitudes I don apos;t know (editor will assign section). BMC Evolutionary Biology (2013) doi:10.1186/1471-2148-13-144
Raj M Srilakshmi et al., A general linear model-based approach for inferring selection to climate Human population genetics. BMC Genetics (2013) doi:10.1186/1471-2156-14-87
Ascencio-Montiel de Jesús Iván et al., SOD2 gene Val16Ala polymorphism is associated with macroalbuminuria in Mexican Type 2 Diabetes patients: a comparative study and meta-analysis Genetic epidemiology and genetic associations. BMC Medical Genetics (2013) doi:10.1186/1471-2350-14-110
Esnaola Mikel et al., A flexible count data model to fit the wide diversity of expression profiles arising from extensively replicated RNA-seq experiments Transcriptome analysis. BMC Bioinformatics (2013) doi:10.1186/1471-2105-14-254
Wormald Samuel et al., Association of candidate single nucleotide polymorphisms with somatic mutation of the epidermal growth factor receptor pathway Prognostics and diagnostics/biomarkers. BMC Medical Genomics (2013) doi:10.1186/1755-8794-6-43
More about the resource:
The International HapMap Project is a collaborative international effort of over 24 groups in six countries to identify and catalog human variation. The project has cataloged most of the probably 10 million SNPs estimated to occur in the Human Genome. The HapMap website includes a browser to view the SNP, haplotype, linkage disequilibrium and tag SNP data, an advanced search tool and software for deeper analysis. All data and tools are free and in the public domain.
The materials and slides offered can not be resold or used for profit purposes. Reproduction, distribution and/or use is strictly limited to instructional purposes only and can not be used for for monetary gain or wide distribution.
Copyright 2009, OpenHelix, LLC.