HapMap, a database and analysis resource of human variation
Tutorial and training materials by OpenHelix
|Learn to use HapMap, a database and analysis resource of human variation. The HapMap project identified and cataloged genetic variation in human beings in four populations with African, Asian, and European ancestry. This freely available database and variation browser contains much of the known variation of the Human genome and researchers can use the data to determine variations that affect health, disease, and individual responses to medications and environmental factors. Learn to use the genome browser associated with this project to view HapMap data, retrieve genotypes and find frequencies for genomic regions.|
- to find SNPs of interest with advanced searching
- how to determine linkage disequilibrium between SNPs
- how to find candidate tag SNPs to better design genotyping assays
- where to download and how to use the HaploView software for deeper SNP analysis
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Recent BioMed Central research articles citing this resource
Mankad Pankaj et al., Alarming findings about genomics of sudden cardiac arrest in India Proceedings of the International Conference on Human Genetics and 39th Annual Meeting of Indian Society of Human Genetics International Conference on Human Genetics and 39th Annual Meeting of the Indian Society of Human Genetics (ISHG). Molecular Cytogenetics (2014) doi:10.1186/1755-8166-7-S1-P102
Liu Mingming et al., Quantitative prediction of the effect of genetic variation using hidden Markov models Sequence analysis (methods). BMC Bioinformatics (2014) doi:10.1186/1471-2105-15-5
Cukier N Holly et al., Exome sequencing of extended families with autism reveals genes shared across neurodevelopmental and neuropsychiatric disorders. Molecular Autism (2014) doi:10.1186/2040-2392-5-1
Reid G Jeffrey et al., Launching genomics into the cloud: deployment of Mercury , a next generation sequence analysis pipeline Sequence analysis (methods). BMC Bioinformatics (2014) doi:10.1186/1471-2105-15-30
Hulsman Hanna L Lauren et al., Identification of a major locus interacting with MC1R and modifying black coat color in an F 2 Nellore-Angus population. Genetics Selection Evolution (2014) doi:10.1186/1297-9686-46-4
More about the resource:
The International HapMap Project is a collaborative international effort of over 24 groups in six countries to identify and catalog human variation. The project has cataloged most of the probably 10 million SNPs estimated to occur in the Human Genome. The HapMap website includes a browser to view the SNP, haplotype, linkage disequilibrium and tag SNP data, an advanced search tool and software for deeper analysis. All data and tools are free and in the public domain.
The materials and slides offered can not be resold or used for profit purposes. Reproduction, distribution and/or use is strictly limited to instructional purposes only and can not be used for for monetary gain or wide distribution.
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