NCBI's SNP database
Tutorial and training materials by OpenHelix
|Learn to use the dbSNP resource, a large and valuable NCBI database that serves both as a repository for genomic variation data (including single nucleotide polymorphisms, microsatellites and small insertion/deletion mutations) and as a computational analysis resource. Learning to mine the dbSNP data will provide the researcher with extensive data and information about variations, evolution, disease and more. Understanding the structure of rs identifiers and ss identifiers will provide important conceptual features of SNP stored records within dbSNP and at other sites that employ dbSNP data. Access points from the dbSNP and the EntrezSNP interface will be explored.|
- how to query the database by SNP attributes, submitter and other information
- how to understand the contents of the rsID records and ssID records
- where to find detailed information about individual variations
- how to accomplish additional search types of the database
Recent BioMed Central research articles citing this resource
Giardina Emiliano et al., Common sequence variants in the LOXL1 gene in pigment dispersion syndrome and pigmentary glaucoma Glaucoma. BMC Ophthalmology (2014) doi:10.1186/1471-2415-14-52
Matthys Christophe et al., Genes and nutrition, is personalised nutrition the next realistic step Proceedings of the Fourth Belgian Nutrition Society Symposium 2014: Genes and nutrition, is personalised nutrition the next realistic step? Genes and nutrition, is personalised nutrition the next realistic step?. Archives of Public Health (2014) doi:10.1186/2049-3258-72-S1-I1
Yang Shanshan et al., CONSTANS is a photoperiod regulated activator of flowering in sorghum Genetics and crop biotechnology. BMC Plant Biology (2014) doi:10.1186/1471-2229-14-148
Jajodia Ajay et al., Glutamate transporter genes are associated with schizophrenia in South Indian population Proceedings of the International Conference on Human Genetics and 39th Annual Meeting of Indian Society of Human Genetics International Conference on Human Genetics and 39th Annual Meeting of the Indian Society of Human Genetics (ISHG). Molecular Cytogenetics (2014) doi:10.1186/1755-8166-7-S1-P42
Chow Keng-See et al., RNA sequencing read depth requirement for optimal transcriptome coverage in Hevea brasiliensis. BMC Research Notes (2014) doi:10.1186/1756-0500-7-69
More about the resource:
dbSNP is one of the many useful resources supported by the National Center for Biotechnology Information, or NCBI, and acts as a repository for individual submissions from labs and institutions, and provides interfaces to search, retrieve, and display a wealth of information about variation in many species. Additionally, reference variation data is computed from the entire database of individual variation submissions. dbSNP can be browsed or queried in several ways, including basic searches on submission type, SNP attributes, submitter information and much more. Additionally, there is advanced searching using the Entrez system.
The materials and slides offered can not be resold or used for profit purposes. Reproduction, distribution and/or use is strictly limited to instructional purposes only and can not be used for for monetary gain or wide distribution.
Copyright 2009, OpenHelix, LLC.