NCBI's SNP database
Tutorial and training materials by OpenHelix
|Learn to use the dbSNP resource, a large and valuable NCBI database that serves both as a repository for genomic variation data (including single nucleotide polymorphisms, microsatellites and small insertion/deletion mutations) and as a computational analysis resource. Learning to mine the dbSNP data will provide the researcher with extensive data and information about variations, evolution, disease and more. Understanding the structure of rs identifiers and ss identifiers will provide important conceptual features of SNP stored records within dbSNP and at other sites that employ dbSNP data. Access points from the dbSNP and the EntrezSNP interface will be explored.|
- how to query the database by SNP attributes, submitter and other information
- how to understand the contents of the rsID records and ssID records
- where to find detailed information about individual variations
- how to accomplish additional search types of the database
Recent BioMed Central research articles citing this resource
Ascencio-Montiel de Jesús Iván et al., SOD2 gene Val16Ala polymorphism is associated with macroalbuminuria in Mexican Type 2 Diabetes patients: a comparative study and meta-analysis Genetic epidemiology and genetic associations. BMC Medical Genetics (2013) doi:10.1186/1471-2350-14-110
Pan Xiaolin et al., A functional polymorphism T309G in MDM2 gene promoter, intensified by Helicobacter pylori lipopolysaccharide, is associated with both an increased susceptibility and poor prognosis of gastric carcinoma in Chinese patients Genetics, genomics and epigenetics. BMC Cancer (2013) doi:10.1186/1471-2407-13-126
Mendes Cristina et al., Genetic diversity and signatures of selection of drug resistance in Plasmodium populations from both human and mosquito hosts in continental Equatorial Guinea. Malaria Journal (2013) doi:10.1186/1475-2875-12-114
Raj M Srilakshmi et al., A general linear model-based approach for inferring selection to climate Human population genetics. BMC Genetics (2013) doi:10.1186/1471-2156-14-87
Yang Chia-Chun et al., Discovering chromatin motifs using FAIRE sequencing and the human diploid genome Transcriptomics. BMC Genomics (2013) doi:10.1186/1471-2164-14-310
More about the resource:
dbSNP is one of the many useful resources supported by the National Center for Biotechnology Information, or NCBI, and acts as a repository for individual submissions from labs and institutions, and provides interfaces to search, retrieve, and display a wealth of information about variation in many species. Additionally, reference variation data is computed from the entire database of individual variation submissions. dbSNP can be browsed or queried in several ways, including basic searches on submission type, SNP attributes, submitter information and much more. Additionally, there is advanced searching using the Entrez system.
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