NCBI's SNP database
Tutorial and training materials by OpenHelix
|Learn to use the dbSNP resource, a large and valuable NCBI database that serves both as a repository for genomic variation data (including single nucleotide polymorphisms, microsatellites and small insertion/deletion mutations) and as a computational analysis resource. Learning to mine the dbSNP data will provide the researcher with extensive data and information about variations, evolution, disease and more. Understanding the structure of rs identifiers and ss identifiers will provide important conceptual features of SNP stored records within dbSNP and at other sites that employ dbSNP data. Access points from the dbSNP and the EntrezSNP interface will be explored.|
- how to query the database by SNP attributes, submitter and other information
- how to understand the contents of the rsID records and ssID records
- where to find detailed information about individual variations
- how to accomplish additional search types of the database
Recent BioMed Central research articles citing this resource
Pustovrh Gašper et al., Molecular phylogeny of Salmo of the western Balkans, based upon multiple nuclear loci. Genetics Selection Evolution (2014) doi:10.1186/1297-9686-46-7
Chemonges Saul et al., Proteogenomics of selective susceptibility to endotoxin using circulating acute phase biomarkers and bioassay development in sheep: a review. Proteome Science (2014) doi:10.1186/1477-5956-12-12
Tsai Yishan et al., CHI3L1 polymorphisms associate with asthma in a Taiwanese population Genetic epidemiology and genetic associations. BMC Medical Genetics (2014) doi:10.1186/1471-2350-15-86
Wang Jingmao et al., Transcriptome profiling of the cold response and signaling pathways in Lilium lancifolium Plant genomics. BMC Genomics (2014) doi:10.1186/1471-2164-15-203
Gupta R Abha et al., Rare deleterious mutations of the gene EFR3A in autism spectrum disorders. Molecular Autism (2014) doi:10.1186/2040-2392-5-31
More about the resource:
dbSNP is one of the many useful resources supported by the National Center for Biotechnology Information, or NCBI, and acts as a repository for individual submissions from labs and institutions, and provides interfaces to search, retrieve, and display a wealth of information about variation in many species. Additionally, reference variation data is computed from the entire database of individual variation submissions. dbSNP can be browsed or queried in several ways, including basic searches on submission type, SNP attributes, submitter information and much more. Additionally, there is advanced searching using the Entrez system.
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