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KEGG, The Kyoto Encyclopedia of Genes and Genomes

Tutorial and training materials by OpenHelix

Learn to use KEGG the Kyoto Encyclopedia of Genes and Genomes, an extensive and widely used resource containing information on genes and pathways in a wide range of species. KEGG curates, integrates, and displays information that enables deep understanding of biological systems. Genes, ligands that interact with genes, pathways in which they participate, descriptive terms that clarify the relationships of all of these aspects come together in this fundamental resource. KEGG is a knowledgebase with application to many areas of biological investigation from basic research, to pharmaceutical discovery, and environmental investigations as well. In this introductory tutorial, you will learn about the foundations and features of KEGG, enabling you to efficiently use one of the foundational resources for systems biology.
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You'll learn:

  • how to navigate KEGG and to perform effective searches on topics of interest
  • how to set the displays for efficient access to the data of interest to you
  • how to customize the colors of displays to represent your own data
  • how to investigate reference and disease pathways, genes, ligands, drugs, and more


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Recent BioMed Central research articles citing this resource

Pop Mihai et al., Diarrhea in young children from low-income countries leads to large-scale alterations in intestinal microbiota composition. Genome Biology (2014) doi:10.1186/gb-2014-15-6-r76

Vitulo Nicola et al., A deep survey of alternative splicing in grape reveals changes in the splicing machinery related to tissue, stress condition and genotype Genomics and evolution. BMC Plant Biology (2014) doi:10.1186/1471-2229-14-99

Krebs Joerg et al., Open lung approach with low tidal volume mechanical ventilation attenuates lung injury in rats with massive brain damage. Critical Care (2014) doi:10.1186/cc13813

Smith E Jonathon et al., Resistance to Botrytis cinerea in Solanum lycopersicoides involves widespread transcriptional reprogramming Plant genomics. BMC Genomics (2014) doi:10.1186/1471-2164-15-334

Wang Joyce et al., Disruption of Mycobacterium avium subsp. paratuberculosis -specific genes impairs in vivo fitness Prokaryote microbial genomics. BMC Genomics (2014) doi:10.1186/1471-2164-15-415

More about the resource:

KEGG is developed and maintained by the Kanehisa Laboratories. From the first reference in 1996, KEGG has grown beyond the initial focus on metabolic pathway data to integrate more data types and important aspects of biology and biomedical research. They continue to add new data types and representations today. Academic users may freely use the KEGG website. To employ KEGG in commercial tools and applications, a license is required. Licenses can be obtained from Pathway Solutions.


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