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KEGG, The Kyoto Encyclopedia of Genes and Genomes

Tutorial and training materials by OpenHelix

Learn to use KEGG the Kyoto Encyclopedia of Genes and Genomes, an extensive and widely used resource containing information on genes and pathways in a wide range of species. KEGG curates, integrates, and displays information that enables deep understanding of biological systems. Genes, ligands that interact with genes, pathways in which they participate, descriptive terms that clarify the relationships of all of these aspects come together in this fundamental resource. KEGG is a knowledgebase with application to many areas of biological investigation from basic research, to pharmaceutical discovery, and environmental investigations as well. In this introductory tutorial, you will learn about the foundations and features of KEGG, enabling you to efficiently use one of the foundational resources for systems biology.
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You'll learn:

  • how to navigate KEGG and to perform effective searches on topics of interest
  • how to set the displays for efficient access to the data of interest to you
  • how to customize the colors of displays to represent your own data
  • how to investigate reference and disease pathways, genes, ligands, drugs, and more


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Recent BioMed Central research articles citing this resource

Song Hoon Kwang et al., Sho-saiko-to, a traditional herbal medicine, regulates gene expression and biological function by way of microRNAs in primary mouse hepatocytes Basic research. BMC Complementary and Alternative Medicine (2014) doi:10.1186/1472-6882-14-14

Yang Yanfang et al., Genome sequencing and analysis of the paclitaxel-producing endophytic fungus Penicillium aurantiogriseum NRRL 62431 Comparative and evolutionary genomics. BMC Genomics (2014) doi:10.1186/1471-2164-15-69

Aronson E Boaz et al., Spdef deletion rescues the crypt cell proliferation defect in conditional Gata6 null mouse small intestine Transcriptional control of gene expression. BMC Molecular Biology (2014) doi:10.1186/1471-2199-15-3

Lazzi Camilla et al., Transcriptomic clues to understand the growth of Lactobacillus rhamnosus in cheese Microbial biochemistry, physiology and metabolism. BMC Microbiology (2014) doi:10.1186/1471-2180-14-28

Dumontier Michel et al., The Semanticscience Integrated Ontology (SIO) for biomedical research and knowledge discovery. Journal of Biomedical Semantics (2014) doi:10.1186/2041-1480-5-14

More about the resource:

KEGG is developed and maintained by the Kanehisa Laboratories. From the first reference in 1996, KEGG has grown beyond the initial focus on metabolic pathway data to integrate more data types and important aspects of biology and biomedical research. They continue to add new data types and representations today. Academic users may freely use the KEGG website. To employ KEGG in commercial tools and applications, a license is required. Licenses can be obtained from Pathway Solutions.


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