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OpenHelix

A gene expression/molecular abundance repository and a curated, online resource for gene expression data

Tutorial and training materials by OpenHelix

Learn to use the Gene Expression Omnibus, or GEO, which is a valuable resource designed to store high-throughput gene expression and molecular abundance data. GEO acts as a repository for the data, and provides interfaces to search, retrieve, and display a wealth of information about genes in many species. This includes microarray data and many other high-throughput techniques. GEO is one of the many useful resources supported by the National Center for Biotechnology Information, or NCBI.
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You'll learn:

  • efficient ways to query GEO for specific genes or experimental designs
  • how to navigate through GEO output displays to find the specific information you want
  • how to navigate GEO


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Recent BioMed Central research articles citing this resource

Gruel Nadège et al., Polarity gene alterations in pure invasive micropapillary carcinomas of the breast. Breast Cancer Research (2014) doi:10.1186/bcr3653

Wang Cheng et al., Aberrant phenotype and transcriptome expression during fiber cell wall thickening caused by the mutation of the Im gene in immature fiber ( im ) mutant in Gossypium hirsutum L Plant genomics. BMC Genomics (2014) doi:10.1186/1471-2164-15-94

Sun Deqiang et al., MOABS: model based analysis of bisulfite sequencing data. Genome Biology (2014) doi:10.1186/gb-2014-15-2-r38

Levy Aviv et al., Profiling microRNAs in Eucalyptus grandis reveals no mutual relationship between alterations in miR156 and miR172 expression and adventitious root induction during development Plant genomics. BMC Genomics (2014) doi:10.1186/1471-2164-15-524

Gong Haijun et al., Pathway-gene identification for pancreatic cancer survival via doubly regularized Cox regression Selected articles from the Twelfth Asia Pacific Bioinformatics Conference (APBC 2014): Systems Biology The Twelfth Asia Pacific Bioinformatics Conference (APBC 2014). BMC Systems Biology (2014) doi:10.1186/1752-0509-8-S1-S3

More about the resource:

GEO can be browsed or queried in several ways, including basic searches, advanced searches, and using nucleotide sequences to begin a search. GEO contains information about platforms, data series, samples, and more. Analysis tools including clustering features are available. Learning to mine the GEO data will provide the researcher with copious amounts of information about their species, tissues, or genes of interest.


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The materials and slides offered can not be resold or used for profit purposes. Reproduction, distribution and/or use is strictly limited to instructional purposes only and can not be used for for monetary gain or wide distribution.
Copyright 2009, OpenHelix, LLC.

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