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OpenHelix

A gene expression/molecular abundance repository and a curated, online resource for gene expression data

Tutorial and training materials by OpenHelix

Learn to use the Gene Expression Omnibus, or GEO, which is a valuable resource designed to store high-throughput gene expression and molecular abundance data. GEO acts as a repository for the data, and provides interfaces to search, retrieve, and display a wealth of information about genes in many species. This includes microarray data and many other high-throughput techniques. GEO is one of the many useful resources supported by the National Center for Biotechnology Information, or NCBI.
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You'll learn:

  • efficient ways to query GEO for specific genes or experimental designs
  • how to navigate through GEO output displays to find the specific information you want
  • how to navigate GEO


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Recent BioMed Central research articles citing this resource

Wang Jia-Jia et al., The influences of PRG-1 on the expression of small RNAs and mRNAs Multicellular invertebrate genomics. BMC Genomics (2014) doi:10.1186/1471-2164-15-321

Hussainzada Naissan et al., Whole adult organism transcriptional profiling of acute metal exposures in male Zebrafish Toxicology. BMC Pharmacology and Toxicology (2014) doi:10.1186/2050-6511-15-15

Driessen M Terri et al., Genes showing altered expression in the medial preoptic area in the highly social maternal phenotype are related to autism and other disorders with social deficits Cellular and molecular mechanisms. BMC Neuroscience (2014) doi:10.1186/1471-2202-15-11

Meyer Eli et al., Integrating transcriptional, metabolomic, and physiological responses to drought stress and recovery in switchgrass ( Panicum virgatum L.) Plant genomics. BMC Genomics (2014) doi:10.1186/1471-2164-15-527

Hu Xinyang et al., Severe hypoxia exerts parallel and cell-specific regulation of gene expression and alternative splicing in human mesenchymal stem cells Transcriptomic methods. BMC Genomics (2014) doi:10.1186/1471-2164-15-303

More about the resource:

GEO can be browsed or queried in several ways, including basic searches, advanced searches, and using nucleotide sequences to begin a search. GEO contains information about platforms, data series, samples, and more. Analysis tools including clustering features are available. Learning to mine the GEO data will provide the researcher with copious amounts of information about their species, tissues, or genes of interest.


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The materials and slides offered can not be resold or used for profit purposes. Reproduction, distribution and/or use is strictly limited to instructional purposes only and can not be used for for monetary gain or wide distribution.
Copyright 2009, OpenHelix, LLC.

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