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OpenHelix

A gene expression/molecular abundance repository and a curated, online resource for gene expression data

Tutorial and training materials by OpenHelix

Learn to use the Gene Expression Omnibus, or GEO, which is a valuable resource designed to store high-throughput gene expression and molecular abundance data. GEO acts as a repository for the data, and provides interfaces to search, retrieve, and display a wealth of information about genes in many species. This includes microarray data and many other high-throughput techniques. GEO is one of the many useful resources supported by the National Center for Biotechnology Information, or NCBI.
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You'll learn:

  • efficient ways to query GEO for specific genes or experimental designs
  • how to navigate through GEO output displays to find the specific information you want
  • how to navigate GEO


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Recent BioMed Central research articles citing this resource

Cava Claudia et al., Combined analysis of chromosomal instabilities and gene expression for colon cancer progression inference. Journal of Clinical Bioinformatics (2014) doi:10.1186/2043-9113-4-2

Almiñana Carmen et al., The battle of the sexes starts in the oviduct: modulation of oviductal transcriptome by X and Y-bearing spermatozoa Non-human and non-rodent vertebrate genomics. BMC Genomics (2014) doi:10.1186/1471-2164-15-293

Romao Moura Josue et al., MicroRNAs in bovine adipogenesis: genomic context, expression and function Non-human and non-rodent vertebrate genomics. BMC Genomics (2014) doi:10.1186/1471-2164-15-137

Camps Carme et al., Integrated analysis of microRNA and mRNA expression and association with HIF binding reveals the complexity of microRNA expression regulation under hypoxia. Molecular Cancer (2014) doi:10.1186/1476-4598-13-28

Zhang Hui et al., Detection of genome-wide copy number variations in two chicken lines divergently selected for abdominal fat content Non-human and non-rodent vertebrate genomics. BMC Genomics (2014) doi:10.1186/1471-2164-15-517

More about the resource:

GEO can be browsed or queried in several ways, including basic searches, advanced searches, and using nucleotide sequences to begin a search. GEO contains information about platforms, data series, samples, and more. Analysis tools including clustering features are available. Learning to mine the GEO data will provide the researcher with copious amounts of information about their species, tissues, or genes of interest.


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The materials and slides offered can not be resold or used for profit purposes. Reproduction, distribution and/or use is strictly limited to instructional purposes only and can not be used for for monetary gain or wide distribution.
Copyright 2009, OpenHelix, LLC.

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