Provides molecular sequence records to help locate gene and protein data.
Tutorial and training materials by OpenHelix
|The RefSeq project, developed and maintained by the National Center for Biotechnology Information (NCBI), provides collected, curated, and consistent non-redundant reference molecular sequence records that help researchers locate important gene and protein data. Processes established by the RefSeq team generate reference sequence sets for many species. RefSeq records link to primary source material, appropriate literature, and additional information from other biomedical resources. Expanded project directions offer more data types. RefSeq, and similar projects with ties to RefSeq, continue to provide quality, reviewed, reference sequences for a variety of projects. RefSeq data can be found in many bioinformatics tools.|
- The history and framework for RefSeq
- How to find and examine RefSeq data at NCBI
- The composition of a typical RefSeq record
- About other project directions and related projects
Recent BioMed Central research articles citing this resource
Pirooznia Mehdi et al., Validation and assessment of variant calling pipelines for next-generation sequencing. Human Genomics (2014) doi:10.1186/1479-7364-8-14
Lucarelli Enrico et al., In vitro biosafety profile evaluation of multipotent mesenchymal stem cells derived from the bone marrow of sarcoma patients Cell, tissue and gene therapy. Journal of Translational Medicine (2014) doi:10.1186/1479-5876-12-95
Chilamakuri Reddy Chandra Sekhar et al., Performance comparison of four exome capture systems for deep sequencing Human and rodent genomics. BMC Genomics (2014) doi:10.1186/1471-2164-15-449
Xie Lan et al., MKL1/2 and ELK4 co-regulate distinct serum response factor (SRF) transcription programs in macrophages Human and rodent genomics. BMC Genomics (2014) doi:10.1186/1471-2164-15-301
Kooper JA Angelique et al., Best diagnostic approach for the genetic evaluation of fetuses after intrauterine death in first, second or third trimester: QF-PCR, karyotyping and/or genome wide SNP array analysis. Molecular Cytogenetics (2014) doi:10.1186/1755-8166-7-6
More about the resource:
The RefSeq project coordinated by NCBI has been providing reference sequence data for more than a decade. This crucial data is found in resources throughout the bioinformatics ecosystem in an extensive range of tools and projects. RefSeq contributes to other reference sequence projects such as RefSeqGene and Locus Reference Genome. Familiarity with RefSeq processes and records will help users to effectively find and understand key features of molecular sequences.
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